Expérimental
Motivated by in vivo observations, we propose to expose active cell populations to well-defined multiscale environments. To achieve these conditions, we will design and fabricate microstructures encompassing several length-scales ranging from subcellular guidance cues to supracellular confinement. Interestingly, these microscale and mesoscale features can act antagonistically or synergistically on the tissue. These experiments will allow quantitative measurements of key physical parameters, such as activity or rheological parameters that can then be related to biological functions.