Internship and thesis proposals
Tissue compaction and shape emergence during chicken axial morphogenesis

Domaines
Biophysics

Type of internship
Expérimental
Description
We are looking for a motivated student willing to join our team to work on an experimental biophysics project where we study the physics of morphogenesis during embryonic body axis development. We investigate the role of mechanics and the cross talk between mechanics and biochemistry in embryonic tissue patterning and emergence of shapes in the context of Active Soft Matter Physics. To understand the minimal physical elements necessary for shape emergence in embryonic tissues, we will setup an in vitro approach mimicking the living conditions and combine micromanipulation techniques, microscopy and image analysis for quantifying the tissue behaviour in various mechanical and chemical conditions. Please see the pdf file for more detail.

Contact
Karine Guevorkian
Laboratory : CCF, Institut Curie -
Team : Dynamic Control of Signaling and Gene Expression
Team Website
/ Thesis :    Funding :